Melissa Spencer, PhD, Chair of the C3 Scientific Advisory Board and Professor of Neurology at UCLA, recently presented during a webinar hosted by the Muscular Dystrophy Association (MDA). The presentation, aimed at educating the public, gave an excellent background about
GRASP-01-003 Natural History Study is recruiting, now through April 30

What is a natural history study? A natural history study is a research study that collects information about the genetics, symptoms, and lived experiences of individuals. These studies are considered observational, because they do not include an interventional drug or therapy,
Travel Grant Program for Early Career Investigators
Coalition to Cure Calpain 3 will award Travel Grants to foster early career investigators who are currently conducting research in the areas of calpainopathies (LGMD2A/R1 and LGMDD4). The grants support travel expenses to attend relevant conferences and meetings to present
New Research Grant: Solving the structure of Calpain 3
C3 is delighted to share that a research grant has been awarded to Dr. Peter Davies of Queen’s University in Ontario, Canada. The project, titled “Solving the structure of Calpain 3 and assessing the impact of LGMD2A/R1,” aims to determine
New Year, New Chair … C3 welcomes Melina Garza to new role as Advocacy Chair
C3 is thrilled to share that Melina Garza is stepping into a newly-created volunteer position. As Advocacy Chair, Ms. Garza will represent our organization educating stakeholders about calpainopathy and engaging them in C3’s mission to drive research toward a treatment
New research grant aims to improve genetic diagnostics in individuals with CAPN3 mutations
C3 is excited to share that a research grant has been awarded to Dr. Svetlana Gorokhova and Dr. Marc Bartoli, Translational Neuromyology Team, Marseille Medical Genetics Institute at Aix Marseille University. The project, “Optimizing the functional assay to identify novel
New Research Grant: Investigating calcium handling modulation as a potential therapeutic for LGMD2A/R1
Coalition to Cure Calpain 3 (C3) is driving LGMD2A/R1 research by awarding a new grant to Dr. Elisabeth Barton, Dr. Lan Wei-LaPierre, and Dr. Siobhan Malany of the University of Florida. The project is titled “Store-operated calcium entry modulation as
Giving Tuesday 2025: Meet Rexton
Over the next few days, we’ll be sharing “LGMD2A/R1 Stories” so you can learn more about the C3 Community as we raise money together to drive scientific research toward a cure for this muscle-wasting disease. Today, meet Rexton: Hi, I’m
Giving Tuesday 2025: Meet Brooklyn
Over the next few days, we’ll be sharing “LGMD2A/R1 Stories” so you can learn more about the C3 Community as we raise money together to drive scientific research toward a cure for this muscle-wasting disease. Today, meet Brooklyn: Hi, my
Giving Tuesday 2025: Meet Walker
Over the next few weeks, we’ll be sharing “LGMD2A/R1 Stories” so you can learn more about the C3 Community as we raise money together to drive scientific research toward a cure for this muscle-wasting disease. Today, meet Walker: Hi, I’m