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New Research Alert: GRASP-001 Study

New data from the GRASP-001 study identify clinical outcome assessments for future LGMD2A/R1 clinical trials A team of LGMD researchers, called the GRASP-LGMD Consortium, published the baseline results of their LGMD2A/R1 clinical outcome study in the Annals of Clinical and Translational Neurology.

Jennifer Levy April 22, 2025April 22, 2025 C3 News, Clinical research study, Research Projects, Uncategorized Read more

Upcoming Event: International LGMD Conference

Don’t miss out on the upcoming International LGMD Conference! Space is limited so register now: https://nationallimbgirdlemusculardystrophyconference.com/ And be sure to join C3 at our complimentary reception! Email us directly at info@curecalpain3.org to reserve your spot by June 30.

Jennifer Levy April 18, 2025April 18, 2025 C3 News Read more

Sarepta Community Update on LGMD Programs

Sarepta Therapeutics recently published a Community Letter to share updates on their limb-girdle muscular dystrophy gene therapy programs. Click here to access the letter on Sarepta’s website. Sarepta is enrolling participants in their LGMD2A/R1 natural history study cohort while simultaneously

Jennifer Levy April 15, 2025April 15, 2025 Uncategorized Read more

Coalition to Cure Calpain 3 and Muscular Dystrophy Association partner to fund gene therapy grant

Muscular Dystrophy Association (MDA) and Coalition to Cure Calpain 3 (C3) partner to fund $300,000 research grant for gene therapy development in limb-girdle muscular dystrophy. This grant supports the work of Melissa Spencer, PhD, Director of the Neuromuscular Division in

Jennifer Levy December 17, 2024December 17, 2024 C3 News, Research Projects, Uncategorized Read more

C3 ANNOUNCES REQUEST FOR APPLICATIONS FOR RESEARCH INTO CALPAINOPATHY

SYNOPSIS Coalition to Cure Calpain 3 (C3) provides funding for research and translational projects to expand the understanding of calpain 3 and Calpainopathy (including LGMD2A/R1 and LGMD1I/D4) to enable development of therapeutic approaches for this disease.  This award is intended

Jennifer Levy November 5, 2024November 5, 2024 C3 News, Funding opportunity, Research Projects Read more

Published Research Alert: Atypical calcium handling in muscles of mouse model of LGMD2A/R1

Limb-Girdle Muscular Dystrophy 2A/R1 (LGMD2A/R1) is caused by changes in a gene called CAPN3, which provides instructions for making a protein called Calpain 3. This protein is specific to skeletal muscle and, among other functions, helps regulate calcium levels inside

Jennifer Levy July 26, 2024July 26, 2024 C3 News, Research Projects Read more

Sarepta Therapeutics recruits for clinical outcomes assessment study

C3 is pleased to share this opportunity on behalf of Sarepta Therapeutics: Sarepta welcomes individuals with LGMD2A/R1 to join a clinical outcomes assessment study. To learn more about the study, visit journeyLGMD.com

Jennifer Levy June 7, 2024June 7, 2024 C3 News, Clinical research study Read more

Volker Straub appointed to C3 Scientific Advisory Board

Volker Straub appointed to C3 Scientific Advisory Board

Coalition to Cure Calpain 3 (C3) is pleased to share that Dr. Volker Straub has been appointed to our Scientific Advisory Board (SAB), joining Dr. Melissa Spencer (Chair), Dr. Kevin Campbell, Dr. Eric Hoffman, and Dr. Louis Kunkel. Professor Volker

Jennifer Levy April 11, 2024April 10, 2024 C3 News Read more

C3 hosts Sarepta to present webinar about the JOURNEY natural history study

Click here to register!

Jennifer Levy March 16, 2024March 16, 2024 C3 News, Clinical research study Read more

C3 attends the 2024 MDA Clinical and Scientific Conference

The Muscular Dystrophy Association held their 2024 Clinical and Scientific Conference on March 3-6 in Orlando, Florida. C3 Scientific Director Dr. Jennifer Levy attended the meeting and shares the following highlights: The MDA Public Policy and Advocacy Team convened representatives

Jennifer Levy March 8, 2024March 8, 2024 C3 News, Research Projects Read more
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Recent Posts

  • Community Health Clinic publishes newsletter focused on LGMDs
  • New Research Alert: GRASP-001 Study
  • Upcoming Event: International LGMD Conference
  • Sarepta Community Update on LGMD Programs
  • C3 Celebrates Rare Disease Day

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