Coalition to Cure Calpain 3

DID YOU KNOW … there are two ways that calpainopathy can be inherited?

DID YOU KNOW … there are two ways that calpainopathy can be inherited? In over 90% of calpainopathy cases, it is inherited in an autosomal recessive manner. This means that it can be passed on through families, and that siblings

C3 Announces Gene Therapy Initiative

PRIME TIME FOR GENE THERAPY While its potential has been discussed and studied for decades, 2017 was a year that showed the promise of gene therapy becoming a reality for patients. The FDA approved the first gene therapies in the

Do you have genetic confirmation of your LGMD diagnosis?

Limb Girdle Muscular Dystrophies (LGMDs) were characterized in the clinic before anyone knew what caused the diseases. Consequently, a bunch of different diseases that all looked the same to physicians were lumped together into one category that they called “LGMD.”

C3 Introduces New Travel Grant Program for Calpainopathy Researchers

Coalition to Cure Calpain 3 (C3) will award Travel Grants to foster early career investigators who are currently conducting preclinical or clinical research in the area of calpainopathy (also known as Limb Girdle Muscular Dystrophy Type 2A or LGMD2A). The

C3 recognizes September 30 “Limb Girdle Muscular Dystrophy Awareness Day” with research grant

Coalition to Cure Calpain 3 (C3) is proud to support September 30 “Limb Girdle MD Awareness Day” with the announcement that we are awarding a new research grant to Dr. Michele Calos, Professor in the Department of Genetics at Stanford

Together we are STRONGER: 3rd annual Limb Girdle Muscular Dystrophy Awareness Day

Limb Girdle Muscular Dystrophy Awareness Day is an annual collaborative effort to globally raise awareness of individuals living with Limb Girdle Muscular Dystrophy (LGMD) and is held on September 30th. The third annual global “Limb Girdle Muscular Dystrophy Awareness Day” will

FDA to step up enforcement of stem cell clinics

Stem cells are cells that have the unique ability to self-renew and to transform into many specialized cell types. They can be isolated either from embryos or from adult tissue. Adult stem cells are being used for various medical therapies

C3 awards research grant to Dr. Rita Perlingeiro to develop gene editing strategy for LGMD2A

Coalition to Cure Calpain 3 (C3) is excited to announce that we are funding a new research project with Dr. Rita Perlingeiro, Professor of Medicine and Lillehei Professor in Stem Cell and Regenerative Cardiovascular Medicine at the University of Minnesota.

Muscle Membrane Serendipity Conference

Key leaders from pharma, academia, and the nonprofit sector convened in Iowa City, Iowa for the Muscle Membrane Serendipity: Past, Present and Future conference on July 20-22, 2017. The invitation-only conference was organized by C3 Scientific Advisory Board member Dr.

International LGMD2A Patient Registry

Clinical studies and trials involve research using human volunteers (also called participants) that is intended to add to medical knowledge. Developing new medicines and treatments is a lengthy and complex process, relying heavily on volunteer participation to help with better